B-lymphocyte antigen CD19 (CD19). Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens.
NCT02465983 - Pancreatic Cancer
The following plot describes the target topology, highlighting the position of the endo-, ecto- and transmembrane domains, as well as the position of a signal peptide, when present. The last three rows describe the position of potential epitopes, as well as phosphorylation and glycosylation sites.